Series episode
| Donnie Wahlberg | ... | Danny Reagan |
| Bridget Moynahan | ... | Erin Reagan-Boyle |
| Will Estes | ... | Jamie Reagan |
| Len Cariou | ... | Henry Reagan |
| Tom Selleck | ... | Frank Reagan |
| Amy Carlson | ... | Linda Reagan |
| Nicholas Turturro | ... | Sgt. Anthony Renzulli |
| Bruce Altman | ... | The Mayor |
| Jessica Collins | ... | Becky Walenski |
| Toby Leonard Moore | ... | Dick Reed |
| Sami Gayle | ... | Nicky Reagan-Boyle |
| Colleen Clinton | ... | Agent Anderson |
| Henry Zebrowski | ... | Hugh Stayton |
| Bianca Amato | ... | Cindy Perry |
| Joey Auzenne | ... | Mondo |
| Michelle Hurst | ... | Councilwoman Collins |
| Tibor Feldman | ... | Chief ME |
| Clark Jackson | ... | Unname character |
| Jennifer Esposito | ... | Jackie Curatola |
| Andrea Roth | ... | Kelly Davidson |
| Tony Terraciano | ... | Jack Reagan |
| Andrew Terraciano | ... | Sean Reagan |
| Abigail Hawk | ... | Detective Melissa Baker |
| Patrick Murney | ... | James Ratchet |
| Preston Simpson | ... | Detective Gerken |
| Hannelore Williams | ... | Rosie Guttierez |
| Erin Mackey | ... | Rachel |
| Rey Lucas | ... | Miguel |
| Mike DiSalvo | ... | Print Reporter |
| Anthony Pierini | ... | Raymondo Jr. |
| Liz Logan | ... | City Official |
| James Schram | ... | Precinct Staff |
| Rosemary Rodriguez | ... | Direction |
| Julie Hébert | ... | Script |