Series episode
Cast: (18 - show/hide all)
| Jonny Lee Miller | ... | Sherlock Holmes |
| Lucy Liu | ... | Dr. Joan Watson |
| Jon Michael Hill | ... | Detective Marcus Bell |
| Aidan Quinn | ... | Captain Thomas Gregson |
| David Harbour | ... | Dr. Mason Baldwin |
| David Costabile | ... | Danilo Gura |
| Ben Rappaport | ... | Dr. Cahill |
| Jenni Barber | ... | Jacqueline Zoltana |
| Anika Noni Rose | ... | Dr. Carrie Dwyer |
| Eric Deskin | ... | Richard Sanchez |
| Jonathan C. Kaplan | ... | Barista Dave |
| Jay Klaitz | ... | Bruce |
| Shauna Miles | ... | Nurse |
| Eric Engleman | ... | Security Guard |
| Rozi Baker | ... | Morgan Duncan |
| Kat Scicluna | ... | Samantha Cropsey |
| Mike Getz | ... | Trent Kelty |
| Shawn Gonzalez | ... | Reporter |
Crew:
| Colin Bucksey | ... | Direction |
| Liz Friedman | ... | Script |