Series episode
Cast: (21 - show/hide all)
| Jonny Lee Miller | ... | Sherlock Holmes |
| Lucy Liu | ... | Dr. Joan Watson |
| Jon Michael Hill | ... | Detective Marcus Bell |
| Aidan Quinn | ... | Captain Thomas Gregson |
| Jill Flint | ... | Alysa Darvin |
| Becky Ann Baker | ... | Pam |
| Frank Wood | ... | EROC Supervisor |
| Candis Cayne | ... | Ms. Hudson |
| Karl Miller | ... | Squatter |
| Bill Buell | ... | Private Maggio |
| Howard McGillin | ... | Davis Renkin |
| Andy Grotelueschen | ... | Nurse Vince |
| Christina Rouner | ... | Denise Castor |
| Curt Bouril | ... | FRP |
| Scott Aiello | ... | Uniform |
| Daniel Loeser | ... | Uniform |
| Slate Holmgren | ... | Uniform |
| Samuel Smith | ... | EMT |
| Nick Sullivan | ... | Frank Dempster |
| Lonnie Quinn | ... | TV Reporter |
| Mark Elliot Wilson | ... | Joseph Leseur |
Crew:
| Andrew Bernstein | ... | Direction |
| Jason Tracey | ... | Script |