Series episode
Cast: (19 - show/hide all)
| Jonny Lee Miller | ... | Sherlock Holmes |
| Lucy Liu | ... | Dr. Joan Watson |
| Jon Michael Hill | ... | Detective Marcus Bell |
| John Noble | ... | Mr. Morland Holmes |
| Aidan Quinn | ... | Captain Thomas Gregson |
| Tim Guinee | ... | Agent McNally |
| Paul Calderon | ... | Zuniga |
| Gary Milner | ... | Mr. Cook |
| Patrick Page | ... | Jonathan Bloom |
| Victor Cruz | ... | Manager |
| David Zayas | ... | Juan Murillo |
| Alia Attallah | ... | Athena |
| Devika Bhise | ... | Minerva |
| Miriam Cruz | ... | Honduran Woman |
| Flora Diaz | ... | Maribel Fonseca |
| Terrell Donnell Sledge | ... | Corrections Officer |
| Gigi Stone | ... | Newscaster |
| Phil Cappadora | ... | Camera Man |
| Marmee Regine Cosico | ... | Hotel Maid |
Crew:
| John Polson | ... | Direction |
| Robert Doherty | ... | Script |