Series episode
Cast: (18 - show/hide all)
| Jonny Lee Miller | ... | Sherlock Holmes |
| Lucy Liu | ... | Dr. Joan Watson |
| Jon Michael Hill | ... | Detective Marcus Bell |
| Desmond Harrington | ... | Michael |
| Aidan Quinn | ... | Captain Thomas Gregson |
| Liza J. Bennett | ... | Hannah Gregson |
| Louis Ozawa Changchien | ... | Go Shinura |
| Robert Capron | ... | Mason |
| Frank Harts | ... | Eddy Dunbridge |
| Deborah S. Craig | ... | Bethany Ito |
| Maurice Jones | ... | Major Joshua Beckham |
| Tony Plana | ... | General Howard Alvero |
| LisaGay Hamilton | ... | Lt. Colonel Robin Deakins |
| Cherelle Cargill | ... | Female Firefighter |
| Comfort Clinton | ... | Maddie |
| Niels Jorgensen | ... | Collins |
| King Victoree | ... | Sumo / martial artist |
| Kyro Wavebourne | ... | Ando Azuma |
Crew:
| Jonny Lee Miller | ... | Direction |
| Jordan Rosenberg | ... | Script |