Series episode
| Patrick Stewart | ... | Jean-Luc Picard |
| Alison Pill | ... | Dr. Agnes Jurati |
| Isa Briones | ... | Dahj / Soji |
| Harry Treadaway | ... | Narek |
| Brent Spiner | ... | Data |
| Orla Brady | ... | Laris |
| David Carzell | ... | Dahj's Boyfriend |
| Merrin Dungey | ... | Interviewer |
| Jamie McShane | ... | Zhaban |
| Sumalee Montano | ... | Mother |
| Maya Eshet | ... | Index |
| Douglas Tait | ... | Tellarite |
| Jon Ian Dredge | ... | Passerby |
| Matt Freeman | ... | Star Fleet Commander |
| Arlene Rodrigez-Lopez | ... | Trill Assistant |
| Richard Scott | ... | Armenian Businessman |
| Hanelle M. Culpepper | ... | Direction |
| Michael Chabon James Duff Akiva Goldsman Alex Kurtzman Kirsten Beyer | ... | Script |