| Nina Siemaszko | ... | Kathleen (2 episodes) |
| Christopher Wiehl | ... | Jeffrey (2 episodes) |
| Geffri Maya Hightower | ... | Maya Bennett (2 episodes) |
| David Sutcliffe | ... | Officer Kevin Nelson (2 episodes) |
| James Pickens Jr. | ... | Dr. Richard Webber (1 episode) |
| Bruce Nozick | ... | Bill Henderson (1 episode) |
| Stacy Edwards | ... | Maria Wilson (1 episode) |
| Rebecca Mader | ... | Leslie (1 episode) |
| Moon Unit Zappa | ... | Jenny (1 episode) |
| Max Arciniega | ... | Paul (1 episode) |
| Marcella Lentz-Pope | ... | Lucy Henderson (1 episode) |
| Matt Riedy | ... | Ken Wilson (1 episode) |
| Ming Lo | ... | Lawyer (1 episode) |
| Noah Dahl | ... | Video Play Back Kid (1 episode) |
| Johnny Cley Rivers | ... | Doctor (1 episode) |
| Dorian Harewood | ... | Duncan Stinson (1 episode) |
| Sean O'Bryan | ... | Dave Walker (1 episode) |
| Barbara Eve Harris | ... | Melinda Stinson (1 episode) |
| Jean Sincere | ... | Gloria Walker (1 episode) |
| Susan Kelechi Watson | ... | Beth (1 episode) |
| Tracey McCall | ... | Ginger (1 episode) |
| Elimu Nelson | ... | Greg O'Brien (1 episode) |
| Drew Osborne | ... | Stevie Walker (1 episode) |
| Elizabeth Pan | ... | ER Nurse (1 episode) |
| Paull Walia | ... | Delivery Guy (1 episode) |
| Molly Hagan | ... | Karen Adams (1 episode) |
| Andy Milder | ... | Doug Adams (1 episode) |
| Stacey Travis | ... | Paige Merring (1 episode) |
| Karley Scott Collins | ... | Erin (1 episode) |
| Amanda Pace | ... | Becky (1 episode) |
| Rachel Pace | ... | Kim (1 episode) |
| Ellery Sprayberry | ... | Sasha (1 episode) |
| Sonia Bril Navarro | ... | Nurse (1 episode) |
| Mageina Tovah | ... | Rebecca Hobart (1 episode) |
| Debra Mooney | ... | Sylvie (1 episode) |
| George Coe | ... | Stan (1 episode) |
| Dinah Lenney | ... | Mrs. Hobart (1 episode) |
| Parisa Fitz-Henley | ... | Cami Davis (1 episode) |
| Miles Heizer | ... | Michael (1 episode) |
| Allen Lulu | ... | Louis (1 episode) |
