Series info
| Thomas Gibson | ... | Aaron Hotchner (5 episodes) |
| Shemar Moore | ... | Derek Morgan (5 episodes) |
| Matthew Gray Gubler | ... | Dr. Spencer Reid (5 episodes) |
| Kirsten Vangsness | ... | Penelope Garcia (5 episodes) |
| Mandy Patinkin | ... | Jason Gideon (4 episodes) |
| Lola Glaudini | ... | Elle Greenaway (4 episodes) |
| A.J. Cook | ... | Jennifer 'JJ' Jareau (4 episodes) |
| Lukas Haas | ... | Clerk (The Footpath Killer) (2 episodes) |
| DJ Qualls | ... | Richard Slessman (1 episode) |
| Meredith Monroe | ... | Haley Hotchner (1 episode) |
| Andrew Jackson | ... | Tim Vogel (1 episode) |
| Chelah Horsdal | ... | Heather Woodland (1 episode) |
| David Lewis | ... | David Woodland (1 episode) |
| Louise Grant | ... | Mrs. Slessman (1 episode) |
| Hiro Kanagawa | ... | Seattle ASAC (1 episode) |
| Leanne Adachi | ... | College Student (1 episode) |
| Kirsten Alter | ... | Brick Agent (1 episode) |
| Kwesi Ameyaw | ... | SPD Officer (1 episode) |
| Trevor Beeby | ... | SWAT Soldier (1 episode) |
| Artine Brown | ... | SPD Detective Holmes (1 episode) |
| G. Michael Gray | ... | Unsub (1 episode) |
| Jeff Hephner | ... | Boy in Image (1 episode) |
| Natalina Maggio | ... | College Student (1 episode) |
| Jamie Mayo | ... | Sister (1 episode) |
| Alonso Oyarzun | ... | FBI Student (1 episode) |
| David Pearl | ... | Cop (1 episode) |
| Malcolm Stewart | ... | Warden (1 episode) |
| Lisa Wegner | ... | FBI Student (1 episode) |
| Joanne Whalley | ... | Karen Donovan (1 episode) |
| J. Karen Thomas | ... | College Admin Tuner (1 episode) |
| Jennifer Hall | ... | Clara (1 episode) |
| Michael David Cheng | ... | Arson Investigator (1 episode) |
| Evan Lee Dahl | ... | Jeremy (1 episode) |
| Sage Mears | ... | 1st Chem Student (1 episode) |
| Kristen Caldwell | ... | 2nd Chem Student (1 episode) |
| Bob Jesser | ... | Professor Wallace (1 episode) |
| Rolando Millet | ... | Campus Security Guard (1 episode) |
| Erika T. Johnson | ... | Agent Trainee (1 episode) |
| Nathanial Moon | ... | 2nd Agent Trainee (1 episode) |
| Christopher Mowod | ... | Campus Patroller (1 episode) |
| J.J. Dashnaw | ... | Matthew Cooke (1 episode) |
| Tim Kelleher | ... | Adrian Bale (1 episode) |
| Jay Acovone | ... | Detective Morrison (1 episode) |
| Tom Virtue | ... | Gil Clurman (1 episode) |
| Caryn West | ... | Mrs. Clurman (1 episode) |
| Indrajit Sarkar | ... | Chicu Reddy (1 episode) |
| Scott Conte | ... | Dan Tracy (1 episode) |
| Asante Jones | ... | Officer Worthy (1 episode) |
| P.J. Marino | ... | Prison Guard (1 episode) |
| Aimee Brooks | ... | Housewife (1 episode) |
| Jeff Davis | ... | Creator(s) |
| 10.01 | X | |
| 10.02 | Burn | |
| 10.03 | A Thousand Suns | |
| 10.04 | The Itch | |
| 10.05 | Boxed In | |
| 10.06 | If the Shoe Fits | |
| 10.07 | Hashtag | |
| 10.08 | The Boys of Sudworth Place | |
| 10.09 | Fate | |
| 10.10 | Amelia Porter | |
| 10.11 | The Forever People | |
| 10.12 | Anonymous | |
| 10.13 | Nelson's Sparrow | |
| 10.14 | Hero Worship | |
| 10.15 | Scream | |
| 10.16 | Lockdown | |
| 10.17 | Breath Play | |
| 10.18 | Rock Creek Park | |
| 10.19 | Beyond Borders | |
| 10.20 | A Place at the Table | |
| 10.21 | Mr. Scratch | |
| 10.22 | Protection | |
| 10.23 | The Hunt |